This is a corrected version of the article that appeared in print. Diseases that present with fever and rash are usually classified according to the morphology of the primary lesion. Rashes can be categorized as maculopapular centrally and peripherally distributed , petechial, diffusely erythematous with desquamation, vesiculobullouspustular and nodular. Potential causes include viruses, bacteria, spirochetes, rickettsiae, medications and rheumatologic diseases. A thorough history and a careful physical examination are essential to making a correct diagnosis. Although laboratory studies can be useful in confirming the diagnosis, test results often are not available immediately.
Immunoglobulin M for measles was positive in this patient, with a titer ratio of 3. Immunoglobulin G for measles was negative. Key to diagnosis is the characteristic rash, which appears about 4 days after the onset of fever. It is an erythematous, maculopapular, confluent rash, which first appears over the face and spreads in a cephalocaudal direction, along with coryza and conjunctivitis Figure 1 [ 1 , 2 ]. The appearance of diarrhea and mild thrombocytopenia also supports the diagnosis.
If your child has a sore throat and a rash, it may be scarlet fever also called scarlatina. If your child has scarlet fever, antibiotics can help your child feel better faster and prevent long-term health problems. Antibiotics can also help protect others from getting sick. Bacteria called group A Streptococcus or group A strep cause scarlet fever.
If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus. Key Clinical Questions What are the most common causes of fever and rash in the hospitalized patient? What is the pathophysiology of fever and rash? What other clinical symptoms and findings are associated with fever and rash?